BCLC is different. Barcelona clinic liver cancer (BCLC) staging uses a set of criteria to guide the management of patients with hepatocellular carcinoma (HCC). trend is probably due to the spread of obesity and diabetes. In this type of wager, the bettor has correctly pick which team will win or lose by a specific amount of points. Different parts of the country offer similar games like Proline, Point Spread and Pools. 5 points (14) Moneyline: North Carolina wins as -132 favorite (bet $10 to win $17. Point Spread (Handicap) bets In the event that the outcome of a ‘Point Spread’ (handicap) Selection Settles on the exact spread (line) offered in a bet, that Selection is deemed. Scratch & Win. Of those, PVI and ES are. 2 months) or. Lotto Max. BCLC stage 0 is a localized circumscribed tumor <. Without a point spread, bettors have to risk a bit more to bet the favorite, but you earn a. Treatment (standard of care) Indication constraints based on tumour burden and liver function. If you have enrolled in BCLC's Voluntary Self-Exclusion/Game Break program please refrain from taking this survey. The aims of this study were to assess the. 5, and 1. Final results include any injury/stoppage time. Moneylines; Totals. Staging of hepatocellular carcinoma (HCC) is necessary for guiding prognostication, management, and research purposes that further aid in the improvement of existing clinical and epidemiological health services. C. LE. Stage 3 liver cancer is divided into 2 further stages - stage 3A. They won back-to-back Grey Cups in 2019 and 2021 (2020 was wiped out by the pandemic) and fell one point short of a three-peat last year when Toronto upset them 24-23. 2%: 46. com . Totals; Player Props. Hepatocellular carcinoma (HCC) is the most common form of liver cancer and accounts for ~90% of. March 3, 2021. Includes the odds, moneyline, and over/under on the current and opening line. You can control point spread by observing the line movement pre-game. You can choose to purchase a Lotto 6/49 ticket with your BC49 play and play the same numbers by selecting “Same numbers for Lotto 6/49”. Moneyline betting is when you pick the winner of the game or event. The BCLC system identifies. The British Columbia Lottery Corporation is a Canadian Crown corporation offering a range of gambling (AKA gaming) products including lottery tickets, casinos and legal online gambling. NFL point spreads even the odds between two teams, offering bettors as close to an even matchup as possible. 2%: 46. The treatment algorithm suggested by the BCLC classification homogenized the surgery group and in turn increased performance of outcome predictability of the BCLC classification. BC/49. If there are 3 outcomes with one being a draw then it is a typical 3-way bet. Point spread betting involves betting on how much a team wins by. Each team has points either added or subtracted from the final score, to then determine if the bet is a winner. The point spread is a handicap placed on the favorite team to even the playing field and make the betting more even. BCLC stage C comprises advanced HCC with vascular invasion, extrahepatic metastasis, and mild cancer-related symptoms or. 5 receptions (-125 on BetMGM): PFF's simulation has Kupp hitting this total and gives this bet a 12. (TV: TBD) Point Spread: New York is a 4. The BCLC staging system consists of individual components, such as performance status, microvascular invasion, extrahepatic spread, and tumor burden. The spread relates directly to the margin of. Barcelona clinic liver cancer-stage C (BCLC-C) encompasses a broad spectrum of tumor burdens, liver function statuses, patient prognoses, and treatment strategies. BC 50/50. C. 00 and the selection will be deemed “Void". 015 and p = 0. 1 This update of the 2018 guidelines incorporates recent, practice changing trials of. In Ontario, the games are called Proline while they are. On the other hand, Baltimore is just 2-2 against the spread as a favorite. 5-point. The point spread is the expected final score difference between two teams. 2 The BCLC algorithm is endorsed by the European and American clinical practice guidelines, 3, 4 whereas in Japan, for example, other guidelines are followed. ET Saturday (ESPN) UPDATE 8:15 P. PROPS final results include OT but not shootouts. Atlanta is 3-0 at home this season and. Overall. Check out these testimonials about our exceptional church loan services. Staging systems assess and describe the extent of tumor burden in the originally primary organ and its spread throughout the body. If you or someone you know. Table. Our analysts research key numbers, matchups, and more to. Select your games and see your potential winnings. Lotto 6/49. A PRO•LINE TIE is an Event tied at the end of regulation play. 5 line). Building off the success of the Giving with Givergy online campaign, BCLC launched Spread the Local Love, focused once again on supporting local charities and businesses, and doubling impact. The estimated survival time is more than 2. Point Spread With Point Spread, uneven matchups can still be a nail biter. The site initially went live in 2004, but it wasn’t until 2010 that it officially became the first casino. Although the BCLC staging system has been endorsed by both the European Association for the Study of the Liver (EASL)4 and the American Association for the Study of Liver Diseases (AASLD),5 several investigators have advocated for extending the resection criteria to select patients with BCLC-B or even BCLC-C HCC;9,10, − 11 For example, Wada and colleagues reported a 5-year overall survival. Example 1. The BCLC B sub-staging system could be an. Marked bridging (portal-to-portal and/or portal-central) with occasional nodule (incomplete cirrhosis) 5. There are different staging systems doctors can use for liver cancer. Get free college football picks for every game of the 2023-24 including college football picks against the spread, straight-up, money line picks, and totals picks (over/under). The BCLC staging system. Action Event where BCLC determines the outcome by any method other than completion of the Sports Action Event. The interest rate is set to 5. 5 OVER (-110) 224. Pittsburgh Steelers at Cleveland Browns: 33. Instant Ticket Game Conditions. In this example it’s called a ‘Win/Draw/Win’ bet, and it’s the first bet featured for soccer games. This includes regulatory oversight of the British Columbia Lottery Corporation (BCLC) (which conducts and manages lotteries, casinos. To calculate the payout of a $50 bet on the Buffalo Bills, divide 115/100 and multiply by $50 (1. Poker Lotto. 5 years. The pandemic undoubtedly has created a variety of. Staging systems in hepatocellular carcinoma. To help, BCLC is launching Spread the Local Love, an online fundraising campaign, running from February 1 to 15. A PRO•LINE TIE occurs when the fight ends in a draw. Keno & Keno Bonus. 16 per 100,000 among women of the same age group. A point spread bets sees the sportsbook add/subtract a number of points to one team’s final score in a matchup between two teams. Same Day Cash Payout*. Several potentially. 2 The BCLC proposal constitutes an evolving approach and it has been regularly updated and refined, incorporating all advancements For most sports, under the PROLINE and PROLINE+ Game Conditions, whenever an event offered for sports betting is postponed or cancelled, the odds for that selection on a bet revert to 1. It is typically diagnosed late in the course of these diseases, and the median survival following diagnosis ranges from approximately 6 to 20. College basketball point spread betting. San Francisco 49ers at Seattle Seahawks: 42. It’s played using a selection slip similar to lottery games with betting options such as Oddset, Point Spread, Over/Under, Props and Toto. 3 months), presence of extrahepatic spread (11. BCLC has continued to take action to address the risk of money laundering. Boston U. The point spread functions as the most popular way to bet on sports. GameSense involves learning how the games work and the odds of winning and losing. 5) cover the spread at home versus the Saints. For example, Super Bowl 56 featured the Cincinnati Bengals taking on the Los Angeles Rams. It stratifies prognosis by integrating albumin-bilirubin score and alpha fetoprotein for additional granularity, particularly for BCLC stage B. 9∼4. Management of HCCMoney Line: Green Bay Packers (+150) ; Pittsburgh Steelers (-175) Total: 38. Methods: A total of 323 consecutive patients in BCLC stage C with PS 1 who had only one tumor and no vascular invasion or extrahepatic spread were enrolled in this retrospective study, regardless of tumor size. for Oddset 2-Outcome: the final outcome of a Sports Action Event listed on the Menu that constitutes either a home Win or a Visitor Win, including extra play, as determined by the applicable Governing Body and verified by BCLC,Point Spread Betting Guide; Prop Betting Guide;. Choose the one that best suits you. The point spread in hockey odds is often referred to as the puck line. V2C 1E2. The screens will guide you through the process of entering the Game Break program. 5 (-110) Gonzaga Bulldogs -2. Over the next 50 years, BCLC was able to help many churches within Texas borders. 1 The BCLC classification includes information related to the. Since 1985, BCLC has been a proud sponsor of events in local communities throughout the province. Localized (cancer is confined to where it started) Regional (cancer has spread to nearby lymph nodes) Distant (cancer has spread to distant body parts) The five-year relative survival rates for liver cancer according to SEER stages are: Localized: 35. Pull Tabs. Based on the. Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. 44 (that was to say, the cut-off point of ALBI score lay in − 2. Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. 2. Introduction. How to Play. 15*$50=$57. In that same example, if the Celtics are -180 against the Hawks, you’d need to bet $180 on the Celtics to win $100 and get $280 back total for your wager. Barcelona clinic liver cancer (BCLC) staging uses a set of criteria to guide the management of patients with hepatocellular carcinoma (HCC). Following the 2018 Barcelona Clinic Liver Cancer (BCLC) guidelines, the BCLC group has provided a 2022 update on the staging, prognosis, and treatment guidelines for hepatocellular carcinoma (HCC), which are used to guide clinical decision making for HCC worldwide. New jackpots every week! LOTTO MAX, Lotto 6/49, BC/49, Daily Grand, Keno and more. The BCLC intermediate stage, or stage B (BCLC-B), includes Child-Pugh A and B patients with large, single-focus HCC (>5 cm) and patients with multifocal HCC, defined as >3 tumors of any size, or 2–3 tumors with a maximal diameter >3 cm. stage B: immediate. veterans Already understand the odds? Fig. BCLC also dedicates a portion of its budget to advance its player health programs that encourage healthy play and improve the safety of products, environments and service for our players. The BCLC staging system has five stages: stage 0: very early stage A: early stage B: immediate stage C: advanced stage D: end-stage For liver cancer in adults,. Purolator courier bag: 2. 4% in BCLCC. This does not reflect BCLC’s current interest rate. Primary liver cancer is a challenging global health concern with an estimated more than a million persons to be affected annually by the year 2025. Pawlik, MD, PhD, MPH, MTS, MBA1 1Department of Surgery, The Ohio State University Wexner Medical Center, James Comprehensive Cancer Center, Columbus, OH; 2Tufts. 5 Opening moneyline: Eagles -280/Jets +230 Opening total: Over/Under 42 points scored Time: 4:25 p. 14 to 0. 2) was constructed by a group of investigators based on the results obtained in the setting of several cohort studies and randomized controlled trials []. Core tip: This is the first study to apply the barcelona clinic liver cancer (BCLC) B subclassification in a survival analysis for hepatocellular carcinoma patients after transarterial embolization. The maximum loan to value permitted is 75%. Point spreads involve a winning margin. GameSense is here to help keep gambling a safe, fun source of entertainment. BCLC stage B (nodules out of Milan criteria without vascular invasion or extrahepatic metastasis, Child-Pugh class A or B, PS 0) is a candidate for TACE. January 31, 2023 1:50 pm by Daniel Thompson. BCLC Introduces New GameSense Advisor to Chances Signal Point. We’re very happy about that. With point spread odds typically being around -110 on either side, a $100 winning bet would return $190. Betting Odds. As reported by Zhao et al. 5 points scored Time: 7 p. The right lung has three lobes, and the left lung has two. Portal vein invasion (PVI) and extrahepatic spread (ES) are two tumor-related factors that define advanced stage in the Barcelona Clinic Liver Cancer (BCLC) staging system (BCLC stage C), and the recommended first line therapy in this stage is sorafenib. 2 months) or. Hepatic resection has the highest local controllability that results in long-term survival for hepatocellular carcinoma (HCC). Nonetheless, the anti-tumoural treatment formally recommended by Western. 9 months). Keno & Keno Bonus. ET. Davidson vs. Scratch & Win. 5 (+105), which means you’ll have to bet $100 to win $105 if your team successfully covers. Hepatocellular carcinoma (HCC) is an aggressive tumor that usually occurs in the setting of chronic liver disease and cirrhosis. It also says one side of the spread hits well. In order for a comparable potential winning payout to a player, more money must be risked to bet the favoured team; less money on the weaker team. Pacific Hold'Em Poker. C. Philadelphia 76ers (10-5. 28 per 100,000 in men under 30 years of age and has risen from 0. As part of the campaign, BCLC sponsored a number of items and gift cards from local businesses. If the spread is set at +7, the underdog must either win the game outright or lose by. Spread bettors are on the unbeaten Eagles, to the. Overtime counts if played, and there are a selection of related betting markets to add extra value, choice and excitement, such as totals, moneyline, winning margin NFL betting, and the like. Sports Action is still running strong and is the offline betting option for BC residents. 75. See: The updated BCLC guidelines are a further step forward in optimizing HCC management. 5) cover by winning by more than 1. 05). O. Using an online sportsbook simplifies the betting process. 3. 5 (-110) Baylor covers by winning the game or by keeping the margin to two points or fewer, such as 69-68. NCAA basketball odds will be released daily, and these betting odds will be refreshed up to the minute on our. 8-3-0 (4-2-0 Away) 31-7-330: O 43: See Game Summary. 2∼33. BC/49 & Extra. 8. Event where BCLC determines the outcome by any method other than completion of the Sports Action Event. 5-catch reception prop a good bet Thursday night. 1. Portal vein invasion (PVI) and extrahepatic spread (ES) are two tumor-related factors that define advanced stage in the Barcelona Clinic Liver Cancer (BCLC) staging system (BCLC stage C), and the. GAMETIME/LOCATION: Rutgers Scarlet Knights (4-5, 1-5 in the Big Ten) at Indiana Hoosiers (2-7, 0. is multinodular and unresectable, advanced stage (C) is the presence of portal invasion or extrahepatic spread, and terminal stage (D) is a. Jackpots of $10-$70 million. (2) Liverpool 1. 5%. 5-point favorites Sunday and stretched to -6. Scratch all of the CALL LETTERS; then scratch all of the letters found in PUZZLES 1 & 2 which match the CALL LETTERS. RC. The. Cirrhosis, probable or definite. Title: Host Local Government Payments for Fiscal Year. However, the tumour burden may be quite heterogeneous in this stage, and prognosis is also influenced by the degree of liver. 888 Sport Bonuses; Top Free Bets and Sign Up Offers. Final results include any injury/stoppage time. Props: Pick the Over or Under or answer Yes or No to a prop question for two to six props. stage A: early. Executive Pastor Emeritus Jamye Cappadonna Grace Point Church. 1 This highlights need for early diagnosis and aggressive therapy in order to improve outcome in this. Or visit our website at. PDF | Over 900,000 people worldwide were diagnosed with liver cancer in 2022 alone, with hepatocellular carcinoma (HCC) accounting for 75–85% of cases. 2. This information must be displayed at point of sale, including all lottery retail outlets; and. Games. Background and AimsThe prognostic value of bile duct invasion (BDI) remains controversial. Typically, diagnosis is late and median survival following diagnosis is approximately 6–20 months. Also known as the "juice" or "vig," if you see NFL Vegas odds of -11. Prior to the two Monday Night games, Week 2 saw underdogs go an impressive 9-3-1 against the spread while. This shows that even with far better online betting options available to residents of WCLC provinces the betting lottery is still bringing in significant revenue at profit margins that are expected to be 30-40% if. If you have enrolled in BCLC's Voluntary Self-Exclusion/Game Break program please refrain from taking this survey. You can Quick Pick or Choose Numbers when playing BC/49. If you combine two spread bets at -110 odds into a two-leg parlay. Vancouver, B. tumor size. m. Vascular invasion, extrahepatic spread: Terminal stage (D) 3-4: C: Any: Stage 0, A, and B, all criteria should be fulfilled. Before you can play the game, you need to learn the game. If you or someone you know has a problem with gambling, please call the Problem Gambling Helpline at 1-888-795-6111. Daily Grand & Extra. . Get free picks & predictions. TACE is standard of care for patients with large single HCC who are not candidates for resection or ablation (BCLC stage A) or for multifocal HCC without evidence of portal vein invasion or extrahepatic spread (BCLC stage B). 0. Currently, sorafenib is the only recommended treatment for patients with BCLC-C and outcomes remain suboptimal. ersial. A + means that team is bet is an underdog. 5) Win Probability: 53. A PRO•LINE TIE occurs when the fight ends in a draw. 5. Lotto 6/49 Game Conditions in effect of Sept 14 2022. From February 1st – 15th, BCLC teamed up with 10 charitable organizations to ‘Spread the Local Love’. 2. As well known, the intermediate stage is defined as multifocal HCC (beyond BCLC-A criteria; see Figure 1) with preserved liver function, no cancer-related symptoms, and no vascular invasion or extrahepatic spread. There are. Poor response rates further hamper outcomes for those that are. 13 A winning bettor will win $100 for every $110 bet. players who appear to be exchanging tickets, chips or cash to cash out; or multiple players who are spread out yet appear to be connected or collaborating based on the observations of staff (BCLC, “BCLC Anti-Money. However, if there has been a conclusive result in a Market at the time of abandonment, all bets on that Market. Management. 0/5. The tumor is smaller than 2 centimeters (cm). According to the BCLC staging system, resection is the first line of11-01-2023 • 11 min read. The Packers are 16-7 ATS as. There are 5 stages to the BCLC staging system. Hepatocellular carcinoma (HCC) is the third most common cause of cancer‐related death worldwide with an increasing incidence. These patients are symptomatic, have vascular invasion, extrahepatic spread, and poor health status. Understand the key concepts that influence the outcome every time you gamble. Pastor Brannan Duncan One Church. A winning $50 moneyline bet on the Bills returns $107. Gilgeous-Alexander leads Oklahoma City against Philadelphia after 40-point performance. radiologic tumour extent. No. (BCLC). Choose the number of sporting events you want to bet on, from 2 to 12. This work demonstrates that the Tumor, Node, Metastasis (TNM) system (8th edition) and the Barcelona Clinic Liver Cancer (BCLC) classification both predict long‐term outcome significantly in patients with hepatocellular carcinoma but that the TNM system (8th edition) predicts long‐term outcome better than. This distinction allowed the development of the first Barcelona Clinic Liver Cancer (BCLC) staging system. Compared to the 2018 version where LT was (only) recommended in multifocal ≤ 3 cm HCCs, three arrows are now directed toward LT, one from each of the following: small multifocal HCCs, a subgroup of BCLC B patients, in case of successful downstaging by TACE or TARE. 3%When gambling stops being fun, help is available. ” Unlike the NFL, the runline will always be 1. Thirty-seven patients without vascular invasion or extrahepatic spread who were classified as BCLC C because of compromised performance status (ECOG 1–2) received HCC therapy according to the number and size of tumors as follows: liver transplant (n=2), resection for a single nodule without portal hypertension (n=5), RFA or PEI (n=9), or. (x) Draw 4. Gonzaga covers by winning by three points or more, such as 75-69. BCLC has sponsored a variety of products and gift cards from local businesses, including Native Shoes, Rocky Point Ice Cream, and Cartems Donuts and made them available on the Spread the Local Love campaign page. This study analyzed survival of BCLC. When the jackpot reaches $50 million, additional $1 million MAXMILLIONS prizes are added. An optimal staging system needs to incorporate the 1) severity of underlying disease, and 2) size and degree of spread of tumor. We can tell you one of the model's strongest Week 6 NFL picks is that the Falcons (-1. With the Lotto! App you can check your lottery tickets anytime, anywhere to see if you’re a winner, or check winning number. Picks are Settled on the official result published by the governing body or as otherwise verified by BCLC. Odds strictly on the straight-up game outcome with no consideration for a point spread. See what's new. C. Point spreads are fairly common in the sports betting industry and well known around the world. A significant increase is also evident among men over 60 [4]. Alternative treatment. You can get a personal discount on new items in our store during 7 days only. 5 points, while a +5. Final results are at the end of the fight. Over/Under: Pick the Over or Under on two to 10 games. We believe in the full deity and the full humanity of Jesus Christ. This system accounts for functional status of the liver and tumor characteristics [24, 25]. In 2021/22, thanks to our players, BCLC generated $1. According to the BCLC staging system, resection is the first line ofHepatocellular carcinoma (HCC) is the most common primary liver cancer and the fourth-leading cause of cancer- related mortality worldwide. To voluntarily self-exclude from PlayNow. To this point, the original BCLC system was updated in 2011 to designate solitary large HCC (≥ 5 cm) as BCLC-A rather than BCLC-B,27 acknowledging that resection, rather than other locoregional therapies,. We aimed to investigate the prognostic value of BDI and the stage of BDI in different staging systems. Point spread: Raiders (-1. The betting line will almost always be different than -110, as 1. Tsilimigras, MD1, Hassan Aziz, MD2, and Timothy M. The Lotto! Certification Program is part of BCLC's commitment to provide you with the information and tools you will need to sell and validate lottery games with integrity. BCLC stage B group patients were distributed from HKLC stage I to III, and BCLC stage C group patients were distributed from HKLC stage II to V. The. (b) “BCLC Point Spread” means the minimum score difference by which the visitor or home is expected to win as assigned to either the home or visitor by BCLC. 5-point favorites for MNF. 124. , if patients in BCLC stage C with PS 1 do not have vascular invasion or extrahepatic spread, more aggressive locoregional therapy could be attempted before choosing a systemic chemotherapy such as sorafenib . 6% (n = 264) presented in BCLC stage A, 47. Contests & Promotions. 6% were in BCLC-B and 52. The expected outcome is expressed as median survival of each tumour stage according to the available scientific evidence. A similar heterogeneity of tumour burden and liver function can be found among patients classified as BCLC stage C, which includes diverse clinical features (performance status [PS] 1–2), macrovascular invasion (MVI) including portal vein tumour (PVT) thrombosis, and/or extra-hepatic spread. McNeese St vs. This is typical of most church lenders and means that the requirement for a church loan is a 25% cash injection by the church into the project. Amit Singal, MD, UT Southwestern Medical Center. Over 48. New to Sports betting?The advanced stage, BCLC stage C, is defined for the group of patients with adverse predictors, which includes patients with cancer-related symptoms, portal vein invasion (PVI), extrahepatic spread (ES), or a combination of these factors, in patients with preserved liver function, defined by Child-Pugh Class A or B . Pacific Hold'Em Poker. 3 hours ago · The Bucs are still trying to close the gap on the NFC South and will need a win over the 5-5 Colts to stay in the race after the Atlanta Falcons play the New Orleans. Purpose: There is a lack of consensus on the surveillance strategy for Barcelona Clinic liver cancer (BCLC) stage B hepatocellular carcinoma (HCC) patients with complete remission (CR). On Wednesday afternoon, the line inched down to Wisconsin -6. “Total O/U” represents the amount. As well known, the intermediate stage is defined as multifocal HCC (beyond BCLC-A criteria; see Figure 1) with preserved liver function, no cancer-related symptoms, and no vascular invasion or extrahepatic spread. Survival analyses were performed using the Kaplan-Meier analysis, and statistical differences between the TACE and sorafenib groups. 14: Player Edge-10. The second novelty in this update is the recognition of liver transplantation (LT) as one of the main objectives. 5 at TwinSpires Sportsbook. The 2022 WCLC Annual Report showed sales revenue of just over $88 million for Sport Select in 2022, up from $65. (g) “OVER/UNDER” means, where applicable, whether the Result of the Sports Action Prop will be greater than (Over) or less than (Under) BCLC’s Pre-set Line for that Sports Action Prop. The point spread may also be referred to as a margin of victory bet, bets against the spread, or simply, the spread. HCC aetiology, macroscopic vascular invasion, extrahepatic spread and portal hypertension, were described using frequency distributions. 95 in payouts for a total of $227. 2 The BCLC proposal constitutes an evolving approach and it has been regularly updated and refined, incorporating all advancementsFor most sports, under the PROLINE and PROLINE+ Game Conditions, whenever an event offered for sports betting is postponed or cancelled, the odds for that selection on a bet revert to 1. At any point, the player may take the Ticket Out and redeem cash from a cash dispenser in the casino or at the cash cage. October 02, 2016. The over/under for total points is set at 234. Compared to the 2018 version where LT was (only) recommended in multifocal ≤ 3 cm HCCs, three arrows are now directed toward LT, one from each of the following: small multifocal HCCs, a subgroup of BCLC B patients, in. Draws every Wednesday and Saturday! Play the lottery in BC and check winning numbers | BCLC Pick up a current Sports Action Point Spread Menu here or at your local Lottery Retailer. Parlay Calculator. Though there are. 0/5. The treatment options for the. Explore Hundreds Of Casinos Games, Check Lotto Numbers & Bet On Your Favourite Teams. The point spread is one of the most popular sports betting options when it comes to betting on college football and the NFL. 4, 5. fixed match correct scores today. Tumor intrinsic subtype directs preferential metastasis to specific organs, with HER2-enriched tumors demonstrating the highest rates of metastasis to the liver, though all subtypes can grow in the liver.